20:04,17,May,2008 | (1030/0/0) | Original
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Wzb by: Moderator flat for a long time that I did not show up in the RP forum, and to make up for the event of default, I am "CNKI" picked up four this year on the published papers on treatment in RP, please my graduate students to convert word documents, for reference (preferably ears.) These articles are published in academic journals, the credibility of relatively larger (such as Professor Xu Guoxing transplant therapy is valuable to explore), and some advertising to promote the surgical treatment and radio health talks in the selling of the so-called drugs, please do not take to heart. Two years ago, when last year I have to, but not the same be taken every year. Now I just take a number of health-care formulations containing lutein and Ginkgo biloba, feeling better than medicine, mapping, surgery even better.
Chinese medicine treatment of 108 patients with retinitis pigmentosa
The world of medicine, 2008.3,261
(Tianquan Chinese Institute of Technology, Vancouver, Canada)
Keywords Retinitis pigmentosa / TCM therapy
Retinitis pigmentosa is a group of inherited retinal degenerative diseases. The main symptoms are night blindness, progressive vision stenosis (tubular vision), vision loss, color vision defects, sensitivity to light, and eventually lead to total blindness. Modern medicine is currently no effective therapy to block the course of development and improvement of their vision in patients. Chinese medicine in the treatment of retinitis pigmentosa has its unique advantages and value. Ancient Chinese medicine diagnosis and treatment of the author inherited the purpose of high wind bird based on the experience gained through the recent Chinese color of the retina
Variability factors and clinical aspects of research, combined with modern medical theory of disease, the latest research and ideas, after 8 years of exploration, the successful development of the "Chinese Tianquan retinal regeneration technology," in the treatment of retinitis pigmentosa made progress.
Tianquan retinal regeneration technology is based on traditional Chinese medicine Chinese medicine mainly to acupuncture, massage, nutrition, physical, psychological treatment, supplemented by the clinical comprehensive treatment technology.
111 Herbal Remedies: The guidance of TCM, this disease is divided into spleen deficiency, liver and kidney, spleen and stomach qi deficiency, blood stasis network, the liver-fire and other 5 syndromes were selected Pill , eyesight Huang Wan, Bu Zhong Yi Qi Tang, Tongqiaohuoxue soup and Danzhi Xiaoyaosan to decoction and tablet-based.
112 Acupuncture: According to the meridian theory, dialectical acupoints to dredge the meridians, and promote the body's yin and yang balance. Acupoints: eyes clear, the ball, save the bamboo, string and wind air, pupil Liao, Yang Bai, Cheng weep, the wind pool, bright, full three years, Sanyinjiao, Taichong, Hegu, Ojo, to Yang, the Gate of Life, liver Yu
113 complementary therapies: massage, moxibustion, infrared radiation, detoxification therapy, psychological counseling, laser irradiation, magnetic, biological desensitization therapy, anti-oxidants, salmon oil, vitamins, trace elements, European and American herbal remedies, diet therapy, physical therapy and so on.
2 Treatment outcome
Since 1999, we Tianquan TCM treatment of retinal regeneration of the 108 cases of patients with retinitis pigmentosa, has made the following clinical effects.
211 central vision improvement: After treatment, the center of the visual acuity improved significantly, depending on the material feels clearer, more distinct black and white, the color more vivid. Some visual acuity increased from 014 to 110.
212 horizons expanded: more performance after treatment expansion in the surrounding field of vision, then the expansion of central visual field. Patients showed less collision phenomenon when walking, wrestling a little, up and down stairs more comfortable with. Can expand the vision of patients with 5 to 10 degrees, field of vision improvement was cumulative.
213 color vision improvement: patients with multiple blue, dark green, black, purple, yellow, brown, blind, can see the before treatment can not distinguish colors such as dark blue and light blue, black and dark green, yellow and white and so on.
214 night vision improved: After treatment, patients can see the road at night, cement steps, you can walk without.
215 to improve dark adaptation: After treatment, from light to dark at the time to adapt to reduced vision. Some patients dropped from the pre-treatment 30min 10min, 5min down some from 2 ~ 3 s.
216 photosensitive and reduce glare and the disappearance of the phenomenon: patients more sensitive to light from time to time in the blazing sun for the phenomenon, see a lot of light scattering, affecting vision. After treatment, the stunning phenomenon of more to improve or even disappear. This is a retinal cell regeneration in the treatment reversed after the performance.
217 ERG (ERGi) Check: After treatment, the ERG showed rod cells and cone cells of a spread b wave amplitude and latency were significantly progress. Some of a spread b wave amplitude after 5 months of treatment increased by 50% ~ 300%, 30Hz flash (white) evoked potential have up to 100% ~ 300% increase.
218 retinal pigmentation spots organic improvement: The fundus photo examination confirmed that patients in the treatment of 1 to 3 years later, the retinal pigmentation spots and patches will be smeared out, smaller, less or even completely disappear.
Reproducibility and clinical effects of 219 long-term effect of the observation: We have treated 108 patients, 85% of the cases have shown a positive treatment response, treatment efficacy has been internationally renowned University of eye examination revealed such as the University of Toronto School of Medicine, University of British Columbia School of Medicine, Calgary University School of Medicine, Duke University School of Medicine, Louisiana University School of Medicine and so on. Our experience shows that regeneration of retinal pigment technology Tianquan clinical results have a high repeatability. After the first treatment in patients with initial onset of more than 7 days in between 1. After 2 weeks in the treatment of most patients can know is valid. Among the 108 patients, 8 patients had achieved clinical cure after treatment, 2 patients 3 years after stopping treatment, visual acuity remained stable. Other 6 patients stopped treatment between 1 to 2 years, visual acuity is also stable.
Medical HEALTH "> Medical>> Eye SCIENCES"> Summary of Chinese medicine treatment of 108 patients with retinitis pigmentosa reviews Recommended online download full collection of paper in the Chinese Institute of Technology, Weidong Tian Quan Vancouver, Canada, "the world of Traditional Chinese Medicine," No. 3, 2008 No. 3 fast-food prizes Survey Abstract: Retinitis pigmentosa is a group of inherited retinal degenerative diseases. The main symptoms are night blindness, progressive vision stenosis (tubular vision), vision loss, color vision defects, sensitivity to light, and eventually lead to total blindness. Modern medicine is currently no effective therapy to block the course of development and improvement of their vision in patients. Chinese medicine in the treatment of retinitis pigmentosa has its unique advantages and value. Succession of the ancient Chinese author Gao Feng bird the purpose of diagnosis and treatment of the basis of experience, number of pages: Page 1 Page Range :162-162 Key words: retinitis pigmentosa treatment efficacy of Chinese medicine subject classification: R774.13 [medicine, HEALTH " Eye SCIENCES "the retina and optic nerve diseases> Retinal Diseases> Retinal degeneration] R274.915.3 [medicine, HEALTH" Chinese Medicine> Journal of Orthopaedics> modern medicine orthopedic diseases] Related articles: subject
Of 140 million dollars of Ottawa researchers led international team to develop gene therapy for retinal blindness
March 8, 2010
Leading vision researchers from Canada and the United States are launching a 5-year, $ 1,400,000 cooperative projects to develop new gene therapy to prevent blindness due to retinal disease. Visual study of Canada's largest private charitable institutions, foundations fighting blindness, is co-funded projects with the Canadian Institutes of Health. The team includes Dr. Kathryn Tsilfidis, senior in the Ottawa Hospital Research Institute and Associate Professor of Medicine University of Ottawa University of Hong Kong scientists led six scientists.
"This project aims to start testing a new gene therapy patients, who have lost their vision after 5 years, due to retinal disease, said Dr.:" Tsilfidis. "This is an ambitious goal, but we think that this is achievable. We very encouraging results to date, our team's dedication and experience to clinics in this issue."
The retina is the inner lining of the eye responsible for detecting light. In North America, millions of people suffering from diseases involving such as retinitis pigmentosa, glaucoma, retinal ischemia and age-related macular degeneration of the retina. Although these diseases for different reasons, but all ultimately the same way: with the retinal nerve cell death, through a process called apoptosis, leading to blindness.
Tsilfidis and her team have shown that the so-called XIAP protein gene can stop this process, and to prevent retinal cell death. The gene can be delivered using eye virus called adeno-associated virus (adenovirus). This therapy has proved, especially in a retinitis pigmentosa, genetic conditions and blindness, one of the outer retina in large part because the loss of an important experimental model for future. XIAP protein in gene therapy can protect the eyes of the dying cells an important part in protecting a significant vision.
"There simply is no treatment to prevent the retinal disease, this is shocking news from blindness to vision loss in more than one million Canadians, said:" Sharon called Currie, President and CEO of the Foundation fighting blindness. "But the prospects for these families is changing to a more hopeful as a new project to save the vision of pioneering research."
"I always wanted to hold out long enough to walk down the aisle, my daughter and not let her make me down the aisle," said David, Ottawa, Hong Kong, who has retinitis pigmentosa. "Maybe no one will notice the difference, but it does not feel the same. This is what I expected."
The new funding will allow Tsilfidis and her colleagues to further improve the XIAP gene therapy clinical trial preparation. Dr. Tsilfidis' former mentor, Dr. Robert Korneluk, will be an important member of the team. Dr. Korneluk Institute found rust XIAP in 1996, he helped develop a cancer therapy based on XIAP is currently in clinical trials. Other members include William excerpts (Florida University), Dr. David Zaks (University of Michigan Kellogg Eye Center) and Dr. Stuart Rand and Brian Leonard science (both in the Ottawa Hospital) from the University of Ottawa Eye Institute. Together, the team in retinal surgery, retinal imaging and gene therapy clinical trials, a wide range of expertise.
In Ottawa, "the researchers have been collaborating, especially in the left found the drug to enter clinical trials, this is a good example of success," said Dr. Deng , CEO and Scientific Director, Aohe Li, Vice President research professor of medicine at the Ottawa Hospital, University of Ottawa. "I am pleased Dr. Tsilfidis research will also benefit from our being through innovative $ 32,000,000 to the construction of high-quality medical interpreters to give us just a year ago received a number of new facilities."
This war, through the blind Foundation project funded by the generosity of Scotiabank donations and private donors to thank.
About the Foundation fighting blindness
The foundation fighting blindness (FFB) is Canada's largest private donations vision research, and its generous donors and long-term annual fund-raising activities for the transfer of visual acuity comics thanks. Since its inception in 1974, FFB has funded dozens of studies found, to determine the genetic forms of blindness universities and hospitals across Canada reason. Today, these findings will help scientists study the idea of a very exciting time, knowledge into vision therapy recovery gift. To stay informed of the progress of Vision Research, signed 'e-news' on our website: www.ffb.ca.
Ottawa Hospital Research Institute
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