20:58,1,Jul,2009 | (1360/0/0) | Original

cholangiocarcinoma prognosis


First, the prognosis of, vary
Cholangiocarcinoma refers to the primary in both ends of the hepatic duct confluence to the common bile duct of the Ministry of extrahepatic bile duct cancer. Obstructive jaundice were the main symptoms of bile duct, often accompanied by itching. About half of the patients in the upper abdomen accompanied by pain and fever, but is generally less severe. Small number of patients, there may be the performance of cholangitis, about half of the patients had loss of appetite and weight loss. Enlarged gallbladder or not, the site differs with cholangiocarcinoma. Swelling of the liver often can be palpable under the ribs or xiphoid, and its hard texture, tenderness not obvious, the latter may be splenomegaly and portal hypertension with ascites and other manifestations.
Primary bile duct cancer is less common, accounting for 0.01% of ordinary autopsy 0.46%, 2% of cancer patients autopsy, biliary tract surgery, 0.3% to 1.8%. Gallbladder bile duct cancer in Europe for the 1.5 to 5 times more than Japan's data are cholangiocarcinoma gallbladder. The male to female ratio of about 1.5 to 3.0. Mostly age 50 to 70 years old, but it can be seen in young people. Prognosis of gallbladder cancer is not ideal, which is a very poor prognosis of patients with cholangiocarcinoma, rarely more than 1 year.
Second, the factors that affect the prognosis of
Of bile duct tumor stage is the most dangerous factors in prognosis, tumor stage later, the prognosis is worse. Late stages of tumor metastasis may indicate. Difficult to be diagnosed early cholangiocarcinoma, patients with advanced treatment are generally so poor prognosis. Cholangiocarcinoma after 5-year survival rate of 0 to 7%, sometimes more than 10% of the reports. 80% of patients died within 1 year after diagnosis.
The overall poor prognosis of cholangiocarcinoma, factors that affect the prognosis of a lot more with cholangiocarcinoma of the location, histological type, metastasis, tumor biology, treatment and so on.
Statistics show that clinical cases, the tumor histological type, TNM stage, lymph node metastasis, liver invasion, pancreatic invasion, surgical margin residual cancer, surgical removal of method, whether to use traditional Chinese medicine and other factors have a major impact on prognosis. Overall, it is early stages, no invasion and metastasis of well differentiated, early treatment with traditional Chinese medicine, and the cutting edge of residual cancer in patients with no better prognosis and survival is longer.
Drug treatment in our hospital to Yao and Yao ethnic medicine medicine as the history of medicine in China, plays an important role in the development of medicine for the nation to lay a substantial foundation, has followed the development of medical history, the progressive development of Yao medicine, uphold the fine tradition absorbing advanced knowledge of modern science. In cancer, Yao drug can alleviate symptoms and s
uffering of cancer patients and improve the quality of life and prolong survival prognosis, reduce cancer mortality, the more the continuation of human development is of great significance.
The key principal is to improve the prognosis of early diagnosis and effective treatment. Foreign reports the survival rate of patients with resectable intrahepatic cholangiocarcinoma average of 18 to 30 months, the 5-year survival rate was 35% to 45%; hepatic hilar cholangiocarcinoma in patients with resectable, the average survival rate was 18 to 24 months , but the 5-year survival rate of only 10%; resectable distal median survival of those 32 to 38 months, 5-year survival rate was 35% to 45%.
Untreated clinical symptoms of cholangiocarcinoma in the mean survival time of about 3 to 4 months, patients in the tumor because of the proliferation of bile duct obstruction caused by recurrent cholangitis, liver failure and death.
Resectable distal bile duct bottom, but most specifically about the survival time of patients depend on individual differences as well as care and rehabilitation situation.
Third, the prognosis of Nursing
Cholangiocarcinoma patients affected by biliary excretion poor digestion and absorption of food, especially the more difficult to digest fatty foods, patients often show poor appetite, eat less, bloating, stool is not transferred. Choose easy to digest and absorb nutritious foods such as fresh fruits and vegetables, eat less or eat high-fat food, ban alcohol and tobacco, drink more water. Necessary to give antiemetic before the meal. Maintaining oral hygiene, to help patients after eating or give oral care mouthwash.
Prescribed intravenous nutritional supplements. Weighed 1 every 3 days. Appropriate activities to explain to patients the need for surgery. Instruct patient to develop a reasonable plan of activities to avoid fatigue. Activities step by step guide patients: the first limbs
cholangiocarcinoma prognosis

Cited reference】 【with China Academic Journal ago 10 1 Geliang; Wu Ho Festival; Majin Liang; Li Jiansheng;; liver resection of the door into the path method high bile duct cancer [J]; Journal of Clinical Surgery; 2006 02 2 Tong Ming Wang, Bo Qiu; resin hemoperfusion treatment of liver hyperbilirubinemia clinical observation [J]; Chinese blood purification; 2005 02 3 Li-Jian Liang, Tang, the Chinese Yun Peng; pancreatic Clinical analysis of 210 cases of resection [J]; Department of General Surgery; 2004 04 4 Cao Liping; Chen Bai-Wen; PENG Shu-you;; jaundice on the impact of pancreaticoduodenectomy analysis [J]; Department of General Surgery ; 2006 07 5 SONG Yu, Li Lu Chuan, Zhan-yuan; obstructive jaundice patients before and after red blood cell immune function and T lymphocyte subsets [J]; of Bases and Clinics; Cai Changchun 1998 02 6 ; Zhang Bing Yuan; Wu Li-Qun; Qiu method for wave; Zhang Shun;; hilar cholangiocarcinoma with severe obstructive jaundice extensive hepatectomy safety retrospective analysis [J]; Hepatobiliary Surgery; 2006 05 7 Xiao-Fang, Zhou Xianting, Sheng-Quan Zou; eight hospitals Analysis of 680 cases of cholangiocarcinoma [J]; Department of General Surgery; 2004 11 8 Shao-fu, Wu Tiecheng, single Yi, Wu, Xiang Wang, Zhao Ping; periampullary 631 cases of clinical manifestations and surgical treatment of pathological [J ]; Journal of Medicine; 2005 08 9 Wang Bin, Lu Chen increase, Zhao Jianxun, Sun Zhanqi; hilar cholangiocarcinoma and evaluation of ultrasound imaging [J]; Chinese Journal of Ultrasonography; 2003 08 10 Zhiqiang; hilar bile duct Surgical treatment of cancer [J]; Lingnan modern clinical surgery; 2002 01
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CD44_v6 and E-cadherin expression and prognosis of cholangiocarcinoma (English) - "Clinical Rehabilitation" 2003 29 The literature sources CNKI www.cnki.net
Objective: To evaluate CD44v6 and E-cadherin (E-cadherin, ED) expression and biological behavior of bile duct cancer. Methods: Immunohistochemistry catalyzed signal amplification method detected 43 cases of cholangiocarcinoma in the expression of CD44v6 and ED, a comprehensive analysis of the expression of CD44v6 and ED with cholangiocarcinoma relationship between clinicopathological factors. Results: In cholangiocarcinoma, CD44v6 and expression rate of ED were 63% and 53%. High expression of CD44v6, ED cholan
giocarcinoma with low expression and TNM stage, histological grade and metastasis (P
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